TIBCO Spotfire Executive to speak at FDA/Industry Statistics Workshop

Somerville, Mass.

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13 September, 2010

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TIBCO Software Inc. (NASDAQ: TIBX) announced today that Dr. Michael O'Connell, senior director of life sciences, TIBCO Spotfire®, will speak at the FDA/Industry Statistics Workshop being held in Washington, D.C. next week. The FDA/Industry Statistics Workshop is sponsored by the ASA Biopharmaceutical Section in cooperation with the FDA Statistical Association.

Participation details regarding the conference are as follows:

What: Dr. Michael O'Connell will present a session titled "Statistically-Guided Review of Safety Data in Clinical Trials." He will also participate in a roundtable discussion on the "Analysis of Clinical Trials."

Session Overview: Assessment of drug safety is a key aspect of drug development. However, clinical trial design is focused on the efficacy endpoints, and safety data analysis is typically an afterthought. During this session, Dr. O'Connell will present statistical and graphical analyses of safety data that enable detailed clinical review of patient-level data. These include recursive partitioning and penalized logistic regression – all displayed in the visual and interactive Spotfire environment. He will also discuss how clinical graphics and interactive data review methods can provide an ongoing coherent and transparent picture of a drug's safety profile for all stakeholders in the development process.

Where: The workshop is being held on September 20-22, 2010 at the Grand Hyatt Washington in Washington, D.C.

When: Dr. O'Connell will participate in the roundtable at 12:00 p.m. and present at 4:15 p.m. local time on Tuesday, September 21, 2010.

Information: For more information about the FDA/Industry Statistics Workshop, visit: http://www.amstat.org/meetings/fdaworkshop/index.cfm?fuseaction=main.

Currently, ten of the top ten global pharmaceutical and biotech companies leverage the TIBCO Spotfire platform to drive shorter development cycles and faster approvals of drugs that are safe and effective. To learn more about TIBCO Spotfire's next generation of life science research products, visit: http://spotfire.tibco.com/spotfire-for-you/by-industry/life-sciences/life-sciences-analytics.aspx.

About TIBCO
TIBCO Spotfire, a product group of TIBCO Software Inc. (NASDAQ: TIBX - News), is a leading provider of enterprise analytics software for next generation business intelligence. TIBCO Spotfire products offer a visual and interactive experience that helps professionals quickly discover new and actionable insights in information. Distinguished by its speed to insight and adaptability to specific business challenges, Spotfire rapidly reveals unseen threats and new opportunities, creating significant economic value. Spotfire customers include industry leaders among the Global 2000 that have deployed Spotfire analytics to gain an information advantage over their competitors. For more information, visit http://spotfire.tibco.com.

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TIBCO, TIBCO Software, TIBCO Spotfire, and Spotfire are trademarks or registered trademarks of TIBCO Software Inc. or its subsidiaries in the United States and/or other countries. All other product and company names and marks mentioned in this document are the property of their respective owners and are mentioned for identification purposes only.

TIBCO Software Inc.

Lindsey Ashjian Torres

Public Relations

+1 650 846 8862

public.relations@tibco.com